Progression of periapical cystic lesion after incomplete endodontic treatment

We report a case of large radicular cyst progression related to endodontic origin to emphasize proper intervention and follow-up for endodontic pathosis. A 25 yr old man presented with an endodontically treated molar with radiolucency. He denied any intervention because of a lack of discomfort. Five years later, the patient returned. The previous periapical lesion had drastically enlarged and involved two adjacent teeth. Cystic lesion removal and apicoectomy were performed on the tooth. Histopathological analysis revealed that the lesion was an inflammatory radicular cyst. The patient did not report any discomfort except for moderate swelling 3 days after the surgical procedure. Although the patient had been asymptomatic, close follow-ups are critical to determine if any periapical lesions persist after root canal treatment.

Production Of Gm-Csf And Tgf-beta 1 In Irradiated Human Gingival Fibroblasts Cultured With Lipopolysaccharide

PURPOSE: Irradiation in the oral cancer patients causes early and late complications such as intraoral mucositis and fibrosis, with a various expression of GM-CSF and TGF-beta. The purpose of this study was to investigate the production of GM-CSF and TGF-beta1 by the irradiated human gingival fibroblasts cultivated with lipopolysaccharide. MATERIALS AND METHODS: Irradiated (total dose, 60 Gy) human gingival fibroblasts were incubated with LPS. Culture supernatants that were collected at 24, 48, and 72 hours were assessed for GM-CSF and TGF-beta1 by enzyme-linked immunosorbent assay. RESULTS: 1. GM-CSF production in nomal gingival fibroblasts was increased with incubation time, but decreased with incubation time in irradiated gingival fibroblasts. GM-CSF production in both normal and irradiated gingival fibroblasts induced with LPS was higher than the control. 2. TGF-beta1 production in normal gingival fibroblasts was decreased after 24 hours, but, it was increased until 48 hours in irradiated gingival fibroblasts. TGF-beta1 production in normal gingival fibroblasts exposed with LPS was higher than the control. Conversely, It was lower than the control in irradiated gingival fibroblasts exposed with LPS. CONCLUSION: This indicates that irradiation in gingival fibroblasts may play an important role in radiation-induced intraoral mucositis and fibrosis. However, LPS decreases the production of TGF-beta1 in the irradiated gingival fibroblasts.

A clinical study on the emergency patients of oral and maxillofacial surgery during recent 5 years

A cephalometric and panoramic analysis of the changes of the condylar position after orthognathic surgery

Quantitative Analysis of Transforming Growth Factor-beta1 in Human Fibroblasts Induced with Staphylococcus enterotoxin B and Lipopolysaccharide

Comparative Study of Panoramic Mandibular Parameters in Postmenopausal Osteoporotic women

Osteoporosis has recently been recognized as a major health problem in the elderly population. The disorder is manifested as a loss of bone mass accompanied by structural alteration of bone and increased incidence of fracture. Mandible also may be affected. So, I evaluated panoramic views of 66 postmenopausal women for finding the possibility of useful diagnostic mandibular parmeters of osteoporosis. To know the correlationship between skeleton and mandible, the average of the bone mineral density of lumbar from 2nd to 4th by the dual energy X-ray absorptiometry(DEXA, LUNAR DPZ. USA), and age and mandibular parameters, that is, the number of residual teeth, alveolar ridge resorption ratio, panoramic mandibular index (PMI), mandibular cortical width (MCW), angular cortical thickness (ACT), ramus cortical thickness (RCT), morphology of mandibular inferior cortical (MIC) were compared. And I divided the all tested women to the osteoporotic group and non-osteoporotic group by the use of T-score-2.0, which was derived from skeletal bone mineral density (BMD). To find the correlationship of the each group with mandibular parameters, t-test and discriminant analysis were done. The results of the t-test were that all parameters were highly related with 2 groups (p<0.05). Especially ACT, MIC, age have had even higher correlationship than others (p<0.001). The results of the discriminant analysis by the use of these ACT, MIC and age were that the discriminant function was Z =-2.973+(-1.447)x(ACT)+1.131x(MIC score)+(0.052)x(age), the cutting score was 0.257 and the classification accuracy was 84.8%. Therefore I suggest that the consideration of the angular cortical thickness (ACT), the age of patient and the morphology of mandibular inferior cortical(MIC) may help find the osteoporosis.

Production of IL-6 and IL-8 in human fibroblasts stimulated with bacterial toxins

Fluticasone Propionate and Beclomethasone Dipropionate in Asthmatic Patients / 결핵

BACKGROUND: Corticosteroid is most potent and effective anti-inflammatory medication currently available and inhaled form has been used in the long-term control of asthma. Fluticasone propionate(Flixotide/Flovent : FP) is highly potent and topically active inhaled corticosteroid and has at least twice the potency of beclomethasone dipropionate(BDP) in the control of asthma. The aim of this study was to compare the efficacy of FP and BDP in several aspects. METHOD: Fifty patients with asthma were treated in a randomized, parallel group study of 4 weeks duration. During 2-week run-in period beta2-agonist was administered. After run-in period, FP 500 micro gram/day was administered via Diskhaler or BDP 800 micro gram/day via reservoir dry-power device. During the run-in and treatment period, morning and evening peak expiratory flow rate(PEFR) were measured daily. Daytime and night-time asthma symptoms, daytime and night-time rescue bronchodilator use were checked daily. FEV1.0 and FVC were measured biweekly in both groups. RESULTS: Three patients treated with FP and seven patient treated with BDP were dropped out. Therefore forty patients completed the study. Morning and evening PEFR was increased and diurnal variation of PEFR decreased significantly in both groups. FEV1.0 increased significantly in FP treatment group but not in BDP group. There were also improvements in daytime and night-time asthma symptoms, daytime and night-time rescue bronchodilator use in both groups after treatment. there were no significant difference between groups in any of the efficacy parameters. Therapeutic effects were dimonstrated earlier in patient treated with FP than BDP. CONCLUSION: In this study, 500 micro gram/day fluticasone propionate was as effective as 800 micro gram/day beclomethasone dipropionate in the control of asthma. Therapeutic effects were demonstrated earlier in patient treated with FP than BDP without adverse effect.

Comparison of Treadmill and Cycle Ergometer in Male Korean College Students / 결핵

BACKGROUND: Generally VO2 max is higher in treadmill exercise than cycle ergometer exercise. According to Hassen and Wasserman, VO2 max with treadmill exercise is higher at ratio of 1.11 than that with cycle ergometer. VO2 max also is influenced by race, sociocultural background, exercise habit. In this study, VO2 max and AT were evaluated between Treadmill and cycle exercise in male Korean college students. METHOD: Study subjects were 44 male college students. We randomized them into 2 groups; 24 students did treadmill exercise at first and 1 week later did cycle ergometer. Another 20 students did in opposite method. They made symptom limited maximal exercise. Author defined maximal exercise as followings: 1) respiratory exchange ratio(RER)>1.1, 2) plateau>30 sec, 3) heart rate reserve(HRR)<15 %, or 4) breathing reserve(BR)<30 %. Otherwise their results are excluded as submaximal exercise. Anaerobic threshold(AT) was estimated by V-slope method. RESULTS: VO2 max and AT was 45.1 +/-6.66 ml/kg/min and 26.0 +/- 6.78 ml/kg/min in treadmill and 34.9 +/- 5.89 ml/kg/min, 19.5 +/- 4.77 ml/kg/min in Cycle Ergometer. The measured-VO2max/pred-VO2max was 98.8 +/- 13.24 % in treadmill; 84.4 +/- 13.42 % in cycle ergometer. Comparing VO2 max in treadmill with that obtained by Hassen's method, there were significant differences.(p<0.01). At maximal exercise HRR, O2/pulse, BR, VE/MVV, VE/VCO2 were higher in treadmill than in cycle but VE/VO2, Vd/Vt, Ti/Ttot were not. At AT O2/pulse, BR, VE/MVV, Ti/Ttot, were higher in treadmill than in cycle, otherwise not. CONCLUSION: According to the result of this study, there are larger gap between treadmill and cycle ergometer in normal Korean adults than foreign data, and it needs further study to obtain reference value of Korea.

Meanings and Indications of pretreatment assessment of esophageal carcinoma with bronchoscopy / 대한내과학회지

OBJECTIVES: To determine the yield of bronchoscopy for evaluating tracheobronchial spread in esophageal carcinoma and to identify the conditions for bronchoscopy in patients with newly diagnosed esophageal carcinoma, who planned to be operated. METHODS: From March 1989 to June 1997, 115 patients with esophageal carcinoma had received bronchoscopy. Bronchoscopic findings were classified into three types: Type I: no definitive endobronchial lesion, Type II: indirect effects(hyperemia and compression), Type III: invasion. CT findings were classified into three classes: Class A: tumor separated from tracheobronchial tree, Class B: abutting tree, Class C: compressing tree. We investigated the correlations of clinical presentation and non-invasive tests (including esophagogram) with bronchoscopic findings. RESULTS: 1) Among 115 patients, bronchoscopic findings were Type I in 67(58.3%), Type II in 34(29.6%), Type III in 14(12.2%). 2) Abnormal bronchoscopic findings are related with length of lesion by esophagogram.(p < 0.05) 3) Class C lesion by chest CT scan were closely correlated with abnormal bronchoscopic findings. 4) Chest symptoms were frequently associated with type III lesion of bronchoscopy CONCLUSION: We could recommend preoperative bronchoscopy in recently diagnosed as esophageal carcinoma who got more than 2 of 3 variables listed below: 1) patients who had chest symptoms, such as cough with sputum, hemoptysis, and dyspnea 2) length of tumor is long in esophagogram(above 5 cm in length), 3) tracheobronchial compressed lesion by chest CT scan. Bronchoscopy is not needed in cases with no chest symptom, short lesion length(below 5 cm) and normal chest CT finding for preoperative evaluation of esophageal carcinoma.

The cervical island flap for intraoral reconstruction following excision of oral cancer: report of 3 cases

Correlation of Gross Appearance or RBCs Numbers with Pleural Histocytology and Pleural Fluid Carcinoembryonic Antigen Values in Malignancy Associated Pleural Effusions / 결핵

BACKGROUND: Most of malignant pleural effusions are serous but 8-33% of them are bloody. We wanted to evaluate the relationships between gross appearance and pleural CEA level or results of histocytology in malignancy associated pleural effusions. We also tried to reevaluate the meaning of CEA measurement in histocylogically proved or unproved malignancy associated pleural effusions. METHODS: We studied 98 cases of malignancy associated pleural effusions, 50 cases of histocylologically proven malignant effusions and 48 cases of histologically unproven paramalignant effusions. We had observed gross appearance and conventional laboratory values and CEA levees for pleural effusions. RESULTS: 44.9% of malignancy associated effusions were bloody(63.6% of bloody effusions were histstocytologically proven malignant effusion). 65.0% of malignancy associated pleural effusions which have RBCs numbers over 100,000/mm3 were cytologically proven malignant effusions. 72.7% of cytologically proven malignant effusions had increased pleural fluid CEA level over 10 ng/ml. 58.2% of cases with pleural CEA over 10ng/ml had positive results in pleural histocytology. There was no definable relationships between pleural fluid CEA elevation and RBCs numbers and results of pleural fluid cytology. CONCLUSION: About half of the cases with malignancy associated pleural effusions were bloody. Histocytologically proven malignant effusions were more common in bloody effusion than non-bloody effusion (63.6% Vs 38.9%). But increased red blood cell numbers was not associated with positivity of pleural histocytology. Pleural fluid CEA elevation(over 10 ng/ml) was not correlated with positive pleural histocytology. But pleural fluid CEA elevation was rare In nonmalignant pleural effusions, and than pleural CEA measurement in uncertain pleural effusions maybe helpful to distinguishes its origin.

A CLINICAL STUDY ON MIDFACIAL FRACTURE

The midface are bounded by a line connecting the two zygomaticofrontal suture, passing through the frontomaxillary and frontonasal suture, and limited below by the occlusal plane of maxillary teeth. Midface fractures include fractures affecting the maxilla, the zygoma, and the nasoorbital ethmoid complex. Midface fractures can be classified as LeFort 1, II, III fractures, sygomaticomaxillary complex fractures, zygomatic arch frationctures, or nasoorbital ethmoid fractures. These injuries may be isolated or occur in combine. And sort tissue injuries to the facial structures are commonly encountered in the treatment of midface fractured patient. Soft tissue wounds may be limited to the superficial structures, but more serious injuries may extend to involve anatomic structures such as the sensory and motor nerves of the face; the parotid, or nasolacrimal glands or ducts ; or the dentoalveolar structures. Especially, these fractures are combined with the orbit, brain injuries and skull base fractures. This is to report the incidence, causes, criteria, complication and treatments of patients who visited our department for midface fracture, for last 10 years.

Cephalometric analysis of postsurgical behavior of mandibular prognathism

No abstract available.

Dacryocystorhinostomy

No abstract available.

Complete remission of maxillary and infratemporal squamous cellcarcinoma after induction chemotherapy

No abstract available.

Clinical Observation of Pediatric Empyema

Seventy cases of empyema treated on the pediatric Service of Kwangju Christian Hospital during 9 years 6 months from Jan. 1970 to Jun. 1979 were analyzed and summerized as follows : 1. Males outnumbered females 38 to 32. No seasonal difference in prevalence was notes. 2. About 60% of empyema(41 cases) were on the right side and 36% on the left side. In 3 cases both sides were affected. The most common concurrent disease was pneumonia, which was suspected as th etiology of empyema. 3. Common chief complaints were dyspnea(53%), fever(47%) and cough(43%). 4. Upon culture of pus, 21 cases among 63 cases(33%) showed no bacterial growth, indicating that had under gone antibacterical treatment before admission. 5. The most common causative organism was Staphylococcus aureus(41.2%) followed vy Pseudomonas(7.9%) Streptococcus(4.8%) E.Coli(4.8%) and Pneumococcus(4.8%). 6. Upon sensitivity test, no resistance was observed to Methicillin and Amikacin, but most of the causative agents were sensitive to Gentamicin, Cephalothin and Novobiocin, while they were least sensitive to Penicillin(17%) and colimycin(9%). 7. Average hospital days were 18, and two cases(2.9%) expired, both one year of age. Average duration of closed drainage was two weeks.

A Case of Apert syndrome(Acrocephaosyndactyly)

Apert syndrome is a rare disorder characterized by malformation of the skull, (usually oxyce-phaly or acrocephaly), in association with sys temic syndactyly It is due to congenital disturbance in the growth of bone and soft tissue affecting principally the head, the hands and the feet. The original description was presented by Troquart in 1886. Since then, more than 200cases have been reported in the world up to 1970. Recently we have seena patient with typical Apert Syndrome and report it here with a brief eviewr of the relevant literature.

A Case of Male Turner Syndrome

We prsent here a 6 year old who has abnormalities of his genitalia, as well as other characteristic features typical of Turner syndrome. He has a small penis with hypospadias, hypolastic testes, and cryptorchi dism. He has short stature, an abnormal looking face, a wide, short webbed neck, and cubitus valgus. He was found to have hydronephrosis and hydroureter on I. V. P. Chromosomal analysis revealed anormal male karyotype with no apparent aberrations.

A Case of Neurofibromatosis without Cafe-au-lait Macule

Almost always patients with multiple neurofibromatosis show cafe-au-lait macules on their skin. At times the skin macules are seen even before the appearance of the neurofibromata in childhood. The author experienced one case of neurofibromatosis in a 12-year-old boy who has no cafe-au-lait macules. Besides the clinical peculiarity of having no skin pigmentation, the histopathology of the case showed well-formed double-palisading structure, which is not common among the micro-scopical findings of neurofibromata.